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J. Bacteriol. doi:10.1128/JB.00258-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Response regulator DegU of Listeria monocytogenes controls temperature-responsive flagellar gene expression in its unphosphorylated state

Norman Mauder, Tatjana Williams, Frederike Fritsch, Michael Kuhn, and Dagmar Beier*

Theodor-Boveri-Institut für Biowissenschaften, Lehrstuhl für Mikrobiologie, Universität Würzburg, Am Hubland, D-97074 Würzburg

* To whom correspondence should be addressed. Email: d.beier{at}biozentrum.uni-wuerzburg.de.


   Abstract

We demonstrate that in Listeria monocytogenes temperature-responsive transcriptional control of flagellar genes does not rely on the phosphorylation of the conserved phosphorylation site (D55) in the receiver domain of response regulator DegU. Furthermore, proper control of DegU-regulated genes involved in ethanol tolerance and virulence is independent of receiver phosphorylation.







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