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Journal of Bacteriology, January 2007, p. 280-283, Vol. 189, No. 1
0021-9193/07/$08.00+0 doi:10.1128/JB.01221-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Influence of Wall Teichoic Acid on Lysozyme Resistance in Staphylococcus aureus
Agnieszka Bera,1,
Raja Biswas,1,
Silvia Herbert,1
Emir Kulauzovic,2
Christopher Weidenmaier,2
Andreas Peschel,2 and
Friedrich Götz1*
Microbial Genetics, University of Tübingen, 72076 Tübingen, Germany,1
Cellular and Molecular Microbiology Division, Medical Microbiology and Hygiene Institute, University of Tübingen, 72076 Tübingen, Germany2
Received 4 August 2006/
Accepted 20 October 2006
Staphylococcus aureus peptidoglycan (PG) is completely resistant to the hydrolytic activity of lysozyme. Here we show that modifications in PG by O acetylation, wall teichoic acid, and a high degree of cross-linking contribute to this resistance.
* Corresponding author. Mailing address: Mikrobielle Genetik, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany. Phone: 0049 7071 2974636. Fax: 0049 7071 295039. E-mail:
friedrich.goetz{at}uni-tuebingen.de.
Published ahead of print on 3 November 2006.
Both authors contributed equally to this work.
Journal of Bacteriology, January 2007, p. 280-283, Vol. 189, No. 1
0021-9193/07/$08.00+0 doi:10.1128/JB.01221-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
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