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J. Bacteriol. doi:10.1128/JB.00015-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

The two-component system CesRK controls the transcriptional induction of cell envelope-related genes in Listeria monocytogenes in response to cell wall-acting antibiotics

Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark; Department of Food Science, University of Copenhagen, Rolighedvej 30, 1958 Frederiksberg C

^* To whom correspondence should be addressed. Email: bhk{at}bmb.sdu.dk.

	Abstract

The two-component system CesRK of Listeria monocytogenes responds to cell wall-acting antibiotics. Here, we show that CesRK controls the transcription of several cell-envelope related genes. The CesRK-dependent induction of these genes may be viewed as an attempt by L. monocytogenes to protect itself against the damaging effects of cell wall-acting antibiotics.